Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.


Advances in Cancer Drug Targets: Volume 1

End User License Agreement (for non-institutional, personal use)

The PIK3CA Gene as a Mutated Target for Cancer Therapy

AKT signaling is activated by VEGF and ANGiopoietins

Heavy metals regulate VEGF and HIF-1α expression via AKT pathway

AKT is the common target inhibited by different natural PRODUCTS with potential chemoprevention effects

Therapeutic perspectives for targeting AKT and mTOR

Inhibitors of Cyclin Dependent Kinases: Useful Targets for Cancer Treatment (An Update)

C-FILP AND THE DEATH RECEPTOR APOPTOSIS PATHWAY

TRANSCRIPTION AND TRANSLATION REGULATION OF C-FILP

C-FILP VARIANTS AS TARGETS FOR CANCER THERAPY

Cellular FLICE-Like Inhibitory Protein (C-FILP ): A Key Anti-Apoptotic Factor and a Target for Cancer Therapy

PIN1: A UNIQUE CANCER TARGET ACTING ON NUMEROUS CANCER-DRIVING PATHWAYS

Pin1: A Promising Novel Diagnostic and Therapeutic Target that Acts on Numerous Cancer-Driving Pathways

INDUCTION OF ANTICANCER IMMUNE REACTIVITY: IMMUNOREGULATORY DENDRITIC CELLS ORCHESTRATE THE DEVELOPMENT OF ANTI-CANCER T CELL REACTIVITY

INDUCTION OF ANTI-CANCER T CELL REACTIVITY BY DENDRITIC CELL VACCINES

THE EFFECTOR PHASE OF ANTICANCER IMMUNITY

IMMUNOSUPPRESSIVE EFFECTS OF CHEMOTHERAPY

REGULATORY T CELLS, TH17 T CELLS AND MESENCHYMAL STROMAL/STEM CELLS - KEY REGULATORS OF ANTICANCER IMMUNE REACTIVITY

ALLOGENEIC STEM CELL TRANSPLANTATION - AN ESTABLISHED COMBINATION OF PROAPOPTOTIC CHEMOTHERAPY AND IMMUNOTHERAPY

Anticancer Immunotherapy in Combination with Proapoptotic Therapy - Possible Therapeutic Strategies for Enhancement of Anticancer Immune Reactivity in Autologous Immunocompetent Cells and After Allogeneic Stem Cell Transplantation

INTRACRINOLOGY OF ESTROGEN DEPENDENT HUMAN BREAST CARCINOMA

MELATONIN AS A SELECTIVE ESTROGEN ENZYME MODULATOR

Melatonin and Breast Cancer: Selective Estrogen Enzyme Modulator Actions

Peripheral neuropathy as a critical limiting factor in anticancer treatment

Cisplatin-induced PN as a paradigm of CIPN

VPA in CDDP-induced PN: two birds with one stone?

Other histone hyper-acetylating strategies: Acetyl-L-carnitine

Targeting Cancer and Neuropathy with Histone Deacetylase Inhibitors

Bentham Science Publishers

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.
Volume nine of the series brings together 7 reviews on a variety of natural products and sources along with a chapter on the basics of investigating antioxidant activity.
Propolis and its key chemical constituents: a promising natural product in therapeutic applications
Investigation of the effects of using omega-3 fatty acids on egg quality in functional egg production 
Quercetin, a flavonoid with remarkable anticancer activity 
Swertiamarin for the treatment of metabolic syndrome
Overview of traditional uses, phytochemistry and pharmacology of Peganum harmala l. 
Investigation of measurement methods of antioxidant activity and involved mechanisms
Recent progress on natural and synthetic flavanone and its derivatives
Role of virgin coconut oil as a multiple health promoting function oil

Frontiers in Natural Product Chemistry: Volume 9

Atta-ur-Rahman

"Frontiers in Clinical Drug Research – Central Nervous System presents the latest researches and clinical studies on the central nervous system (CNS). It covers a range of topics such as the development and pathophysiology of the brain and spinal cord, physiological sites of drug action in the CNS and clinical findings on drugs used to treat CNS defects due to injury or impaired development. In addition to clinical research on humans, the book also highlights other avenues of CNS medicine and research such as pain medicine, stem cell research, pharmacology, toxicology and translational models in animals.   
The first volume of the series features chapters on the following topics: 
-nerve targets in pain medicine
-Spinal cord injury
-Research on neurotoxins targeting voltage gated ion channels
-G protein coupled receptor agonists and modulators
-Drug research on mediating hypoxia in developing white matter"


Frontiers in Clinical Drug Research - Central Nervous System: Volume 1

"Obesity is a complex health problem, caused by a number of factors such as excessive food intake, lack of physical activity, genetic predisposition, endocrine disorders, medications and psychiatric illnesses. Onset of obesity in both the developing and the developed world has reached epidemic proportions. In response to this, efforts to control and treat obesity have also been vigorously pursued, ranging from raising awareness about lifestyle changes to the discovery and development of safe and effective anti-obesity drugs.
Anti-obesity Drug Discovery and Development is focused on this very important area of healthcare research. The third volume of this series is dedicated to anti-obesity treatments including updates on new therapeutics for obesity, Nesfatin-1 and its therapeutic uses, the role of proteomics in pediatric anti-obesity treatment, the role of oxidative stress in childhood obesity and a review of data on gut microbiota as a treatment option for obesity."


Anti-obesity Drug Discovery and Development: Volume 3

Dr. M. lqbal Choudhary 

"Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.
 
This volume presents the following reviews:
Recent Progress on Asymmetric Synthesis of Chiral Flavanones, Chromanones, and Chromenes
Supramolecular Chemistry of Modified Amino Acids and Short Peptides
The Use of Nanocatalysts in the Synthesis of Heterocycles: A Contemporary Approach
Synthesis and Applications of 1,2,3-Triazoles
Ring C–H Functionalization of Aromatic N-Oxides 
 "


Advances in Organic Synthesis: Volume 12

"Frontiers in Clinical Drug Research - Anti-Allergy Agents is a book series comprising of a selection of updated review articles relevant to the recent development of pharmacological agents used for the treatment of allergies. The scope of the reviews includes clinical trials of anti-inflammatory and anti-allergic drugs, drug delivery strategies used to treat specific allergies (such as inflammation, asthma and dermatological allergies), lifestyle dependent modes of therapies and the immunological or metabolic mechanisms that are of interest to researchers as targets for new drugs.
The third volume of this series brings 5 reviews which cover the following topics: H1 receptor selectivity, chronic spontaneous urticaria therapy, smooth muscle cell Ca2+ signaling pathway targeting for asthma therapy, allergic rhinitis and endosomal toll-like receptors.
 
Frontiers in Clinical Drug Research - Anti-Allergy Agents will be of interest to immunologists and drug discovery researchers interested in anti-allergic drug therapy as the series provides relevant cutting edge reviews written by experts in this rapidly expanding field."


Frontiers in Clinical Drug Research - Anti-Allergy Agents: Volume 3

"Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.
Volume eight of the series brings seven reviews covering these main themes: marine natural products, neuroprotective natural products, chromenes, coumarin derivatives, and psychedelics. The chapters featured in this volume are:
- Chemistry, Antiviral Properties and Clinical Relevance of Marine Macroalgae and Seagrass
- Quinolizidine Alkaloids from Marine Organisms: A Perspective On Chemical, Bioactivity and Synthesis
- Towards The Use of Whole Natural Products in Psychedelic Research and Therapy: Synergy, Multi-Target Profiles, and Beyond
- Neuroprotective Effects of Polyphenols
- Neuroprotection with the Functional Herbs from the Lamiaceae Family
- Coumarin Derivatives as Potential Anti-Inflammatory Agents for Drug Development
- Recent Progress in The Synthesis and Biological Activity of Chromene and Its Derivatives
 "


Frontiers in Natural Product Chemistry: Volume 8

"Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
 
This volume of the series focuses on reviews of treatments derived from natural sources (cannabinoid-based medicines and turmeric), immunotherapy, biomarkers for glioblastoma and some new drug targets for anti-cancer treatment.
 
 
 
The reviews included in this volume are:
 
- Cannabinoid-Based Anticancer Strategies:
 
- The Beneficial Effects of Turmeric and Its Active Constituent in Cancer Treatment
 
- Immunotherapy Approaches Focusing on Cancer Stem Cells
 
- Immunotherapy for the Treatment of Hepatocellular Carcinoma
 
- Role of Biomarkers in Developing Therapies for Glioblastoma Multiforme
 
- Poly (ADP-ribose) Polymerases as New Drug Targets in Cancer Treatment"


Frontiers in Anti-Cancer Drug Discovery: Volume 12

"Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine.
 
This volume includes current literature on a variety of topics:
 
-the utility of exogenous and endogenous neural stem cells in spinal cord injury
 
-somatic cells for human induced pluripotent stem cells (iPSCs)
 
-reactive oxygen species (ROS) mediated cellular signaling for stem cell differentiation
 
-the therapeutic potential of microRNAs in cardiac diseases
 
-stem cell therapy for the treatment of malaria"


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 9

Shazia Anjum

"Frontiers in Clinical Drug Research – Anti infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.
The fourth volume of this series features reviews that cover a variety of topics including: 
-Strategies to prolong antibiotic life
-Catalytic antibodies for targeting rabies and influenza viruses
-Antiviral therapies for arenaviruses
-The role of steroids in viral infections
-Monoclonal antibody manufacturing processes
-Prevention and eradication of biofilms in medical devices"


Frontiers in Clinical Drug Research - Anti Infectives: Volume 4

"Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.
The third volume of this book series features six reviews covering structure-property relationship of polyphenols, NMR spectroscopy in breast cancer diagnosis, NMR methods in drug discovery and formulation, protein confirmation analysis using Fluorine NMR and NMR studies enaminones."


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Advances in Cancer Drug Targets: Volume 1

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Atta-ur-Rahman

Frontiers in Natural Product Chemistry: Volume 9

Frontiers in Clinical Drug Research - Central Nervous System: Volume 1

Anti-obesity Drug Discovery and Development: Volume 3

Advances in Organic Synthesis: Volume 12

Frontiers in Clinical Drug Research - Anti-Allergy Agents: Volume 3

Frontiers in Natural Product Chemistry: Volume 8

Frontiers in Anti-Cancer Drug Discovery: Volume 12

Frontiers in Stem Cell and Regenerative Medicine Research: Volume 9

Frontiers in Clinical Drug Research - Anti Infectives: Volume 4

Applications of NMR Spectroscopy: Volume 3

Atta-ur-Rahman