Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.


Advances in Cancer Drug Targets: Volume 1

End User License Agreement (for non-institutional, personal use)

The PIK3CA Gene as a Mutated Target for Cancer Therapy

AKT signaling is activated by VEGF and ANGiopoietins

Heavy metals regulate VEGF and HIF-1α expression via AKT pathway

AKT is the common target inhibited by different natural PRODUCTS with potential chemoprevention effects

Therapeutic perspectives for targeting AKT and mTOR

Inhibitors of Cyclin Dependent Kinases: Useful Targets for Cancer Treatment (An Update)

C-FILP AND THE DEATH RECEPTOR APOPTOSIS PATHWAY

TRANSCRIPTION AND TRANSLATION REGULATION OF C-FILP

C-FILP VARIANTS AS TARGETS FOR CANCER THERAPY

Cellular FLICE-Like Inhibitory Protein (C-FILP ): A Key Anti-Apoptotic Factor and a Target for Cancer Therapy

PIN1: A UNIQUE CANCER TARGET ACTING ON NUMEROUS CANCER-DRIVING PATHWAYS

Pin1: A Promising Novel Diagnostic and Therapeutic Target that Acts on Numerous Cancer-Driving Pathways

INDUCTION OF ANTICANCER IMMUNE REACTIVITY: IMMUNOREGULATORY DENDRITIC CELLS ORCHESTRATE THE DEVELOPMENT OF ANTI-CANCER T CELL REACTIVITY

INDUCTION OF ANTI-CANCER T CELL REACTIVITY BY DENDRITIC CELL VACCINES

THE EFFECTOR PHASE OF ANTICANCER IMMUNITY

IMMUNOSUPPRESSIVE EFFECTS OF CHEMOTHERAPY

REGULATORY T CELLS, TH17 T CELLS AND MESENCHYMAL STROMAL/STEM CELLS - KEY REGULATORS OF ANTICANCER IMMUNE REACTIVITY

ALLOGENEIC STEM CELL TRANSPLANTATION - AN ESTABLISHED COMBINATION OF PROAPOPTOTIC CHEMOTHERAPY AND IMMUNOTHERAPY

Anticancer Immunotherapy in Combination with Proapoptotic Therapy - Possible Therapeutic Strategies for Enhancement of Anticancer Immune Reactivity in Autologous Immunocompetent Cells and After Allogeneic Stem Cell Transplantation

INTRACRINOLOGY OF ESTROGEN DEPENDENT HUMAN BREAST CARCINOMA

MELATONIN AS A SELECTIVE ESTROGEN ENZYME MODULATOR

Melatonin and Breast Cancer: Selective Estrogen Enzyme Modulator Actions

Peripheral neuropathy as a critical limiting factor in anticancer treatment

Cisplatin-induced PN as a paradigm of CIPN

VPA in CDDP-induced PN: two birds with one stone?

Other histone hyper-acetylating strategies: Acetyl-L-carnitine

Targeting Cancer and Neuropathy with Histone Deacetylase Inhibitors

Bentham Science Publishers

"This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.
 
Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.
 
The eighth volume of this series features 8 chapters that cover methods for antimicrobial drug discovery (with 2 chapters that focus on genomics) as well as updates on drug development against Helicobacter pylori and emerging coronaviruses, among other interesting topics:
 
 
 
- Eradication of Helicobacter pylori Infection with Non-Bismuth Quadruple Concomitant Therapy
 
- Drug Discovery Strategies Against Emerging Coronaviruses: A Global Threat
 
- Opportunities Offered By Fragment-Based Drug Design in Antibiotic Development
 
- Phage therapy as a Tool for Control of Foodborne Diseases: Advantages and Limitations
 
- Subtractive Genomics Approaches: Towards Anti-Bacterial Drug Discovery
 
- Recent Advances in the Discovery of Antimicrobials through Metagenomics
 
- Phyto-Nano-Antimicrobials: Synthesis, Characterization, Discovery, and Advances
 
- Aptamers as Anti-infective Agents"


Frontiers in Anti-Infective Drug Discovery: Volume 8

Atta-ur-Rahman

Dr. M. lqbal Choudhary 

"Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field.
 
The ninth volume of this series brings together reviews covering topics related to the treatment of neoplasms, systems biology, respiratory diseases among others.
 
Topics included in this volume are:
 
-Prognostic biomarkers in prostate cancer
-Chemoresistance in cancer cells
-GPCRS in systems and synthetic biology
-Mechanisms of action of ribavirin in different diseases
-Carbon nanotubes and drug targets
-The role of phosphatase I inhibitors in Minkowski spaces
-Phosphodiesterase targeting for treating respiratory diseases
 "


Frontiers in Drug Design & Discovery: Volume 9

"Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.
 
The sixth volume of this series features these interesting reviews:
 
- Direct-acting antiviral drugs for treatment of Hepatitis C virus infection
 
- Plant lattices as anti-infective compounds
 
- Antimicrobial materials and devices for biomedical applications
 
- Recent advances in the treatment of toxoplasmosis
 
- Antimicrobial immunoglobulin prophylaxis and therapy
 
- Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria"


Frontiers in Clinical Drug Research - Anti Infectives: Volume 6

"Frontiers in CNS Drug Discovery is a book series devoted to publishing reviews which highlight the latest advances in drug design and discovery for disorders of the central nervous system (CNS). Eminent scientists write contributions on all areas of CNS drug design and drug discovery, including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series is essential reading for all pharmaceutical scientists involved in CNS drug design and discovery who wish to keep abreast of rapid and important developments in the field.
 
The third volume of this series brings reviews on brain tumor treatment, neurodegeneration, hyperalgesia, cholinesterase inhibition and much more."


Frontiers in CNS Drug Discovery: Volume 3

"Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
 
The tenth volume of the series features chapters covering the following topics:
 
- Challenges in the Management of Hepatoblastoma
 
- The Emerging Role of Monocarboxylate Transporter-1 in Cancer
 
- In-vitro Anti-Proliferative Assays and Techniques Used in Pre-Clinical Anti-Cancer Drug Discovery
 
- Recent Advances in the Development of Mesoporous Anti-Cancer Drug Nanocarriers
 
- Polyphenols and Cancer
 
- Glioblastoma Multiforme
 
- Cutting Edge Targeting Strategies Utilizing Nanotechnology in Breast Cancer Therapy"


Frontiers in Anti-Cancer Drug Discovery: Volume 10

"Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.
The third volume of this book series features six reviews covering structure-property relationship of polyphenols, NMR spectroscopy in breast cancer diagnosis, NMR methods in drug discovery and formulation, protein confirmation analysis using Fluorine NMR and NMR studies enaminones."


Applications of NMR Spectroscopy: Volume 3

"Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research.
The fourth volume of this series features 5 chapters that cover these topics: 
- Design and Synthesis of HIV-1 Protease Inhibitors
- Potential Magnetic Nanotherapeutics for Management of neuroAIDS
- Syntheses of FDA Approved Integrase Inhibitor HIV Drugs and Improved Manufacturing using Flow Processing
- The Development and Clinical Progress on Chemokine Receptor-Based HIV Entry Inhibitors
- Sexually Transmitted Co-infections in Persons Living with HIV"


Frontiers in Clinical Drug Research - HIV: Volume 4

"Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology.
The third volume of this series features 6 reviews: 
-Advances in the understanding and treatment of immune thrombocytopenia
-Recent developments in chronic myeloid leukemia biology and treatment
-Role of immunomodulatory drugs in the treatment of lymphoid and myeloid malignancies
-Pediatric hematological malignancies – clinical manifestation, treatment and follow-up
-Novel therapies and immunotherapeutic approaches to treat childhood leukemia
-Erythrocyte turnover and erythropoietic patterns in two different experimental mouse models of anemia"


Frontiers in Clinical Drug Research - Hematology: Volume 3

"Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology.
 
 
 
The seventh volume of this series features reviews that cover the following topics related to the treatment of neurodegenerative diseases, epilepsy and stroke:
 
-Fatty Acid Amides as a New Potential Therapeutic Agent in Multiple Sclerosis
 
-Epileptic Seizures Detection Based on Non-Linear Characteristics Coupled with Machine Learning Techniques
 
-Hampering Essential Tremor Neurodegeneration in Essential Tremor: Present and Future Directions
 
-The Potential Therapeutic Role of the Melatoninergic System in Treatment of Epilepsy and Comorbid Depression
 
-Modeling Neurodegenerative Diseases Using Transgenic Model of Drosophila
 
-Genetic Basis in Stroke Treatment: Targets of Potent Inhibitors"


Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7

 Zareen Amtul

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.
Volume nine of the series brings together 7 reviews on a variety of natural products and sources along with a chapter on the basics of investigating antioxidant activity.
Propolis and its key chemical constituents: a promising natural product in therapeutic applications
Investigation of the effects of using omega-3 fatty acids on egg quality in functional egg production 
Quercetin, a flavonoid with remarkable anticancer activity 
Swertiamarin for the treatment of metabolic syndrome
Overview of traditional uses, phytochemistry and pharmacology of Peganum harmala l. 
Investigation of measurement methods of antioxidant activity and involved mechanisms
Recent progress on natural and synthetic flavanone and its derivatives
Role of virgin coconut oil as a multiple health promoting function oil

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Advances in Cancer Drug Targets: Volume 1

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About the authors

Atta-ur-Rahman

Frontiers in Anti-Infective Drug Discovery: Volume 8

Frontiers in Drug Design & Discovery: Volume 9

Frontiers in Clinical Drug Research - Anti Infectives: Volume 6

Frontiers in CNS Drug Discovery: Volume 3

Frontiers in Anti-Cancer Drug Discovery: Volume 10

Applications of NMR Spectroscopy: Volume 3

Frontiers in Clinical Drug Research - HIV: Volume 4

Frontiers in Clinical Drug Research - Hematology: Volume 3

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7

Frontiers in Natural Product Chemistry: Volume 9

Atta-ur-Rahman