Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.


Advances in Cancer Drug Targets: Volume 1

End User License Agreement (for non-institutional, personal use)

The PIK3CA Gene as a Mutated Target for Cancer Therapy

AKT signaling is activated by VEGF and ANGiopoietins

Heavy metals regulate VEGF and HIF-1α expression via AKT pathway

AKT is the common target inhibited by different natural PRODUCTS with potential chemoprevention effects

Therapeutic perspectives for targeting AKT and mTOR

Inhibitors of Cyclin Dependent Kinases: Useful Targets for Cancer Treatment (An Update)

C-FILP AND THE DEATH RECEPTOR APOPTOSIS PATHWAY

TRANSCRIPTION AND TRANSLATION REGULATION OF C-FILP

C-FILP VARIANTS AS TARGETS FOR CANCER THERAPY

Cellular FLICE-Like Inhibitory Protein (C-FILP ): A Key Anti-Apoptotic Factor and a Target for Cancer Therapy

PIN1: A UNIQUE CANCER TARGET ACTING ON NUMEROUS CANCER-DRIVING PATHWAYS

Pin1: A Promising Novel Diagnostic and Therapeutic Target that Acts on Numerous Cancer-Driving Pathways

INDUCTION OF ANTICANCER IMMUNE REACTIVITY: IMMUNOREGULATORY DENDRITIC CELLS ORCHESTRATE THE DEVELOPMENT OF ANTI-CANCER T CELL REACTIVITY

INDUCTION OF ANTI-CANCER T CELL REACTIVITY BY DENDRITIC CELL VACCINES

THE EFFECTOR PHASE OF ANTICANCER IMMUNITY

IMMUNOSUPPRESSIVE EFFECTS OF CHEMOTHERAPY

REGULATORY T CELLS, TH17 T CELLS AND MESENCHYMAL STROMAL/STEM CELLS - KEY REGULATORS OF ANTICANCER IMMUNE REACTIVITY

ALLOGENEIC STEM CELL TRANSPLANTATION - AN ESTABLISHED COMBINATION OF PROAPOPTOTIC CHEMOTHERAPY AND IMMUNOTHERAPY

Anticancer Immunotherapy in Combination with Proapoptotic Therapy - Possible Therapeutic Strategies for Enhancement of Anticancer Immune Reactivity in Autologous Immunocompetent Cells and After Allogeneic Stem Cell Transplantation

INTRACRINOLOGY OF ESTROGEN DEPENDENT HUMAN BREAST CARCINOMA

MELATONIN AS A SELECTIVE ESTROGEN ENZYME MODULATOR

Melatonin and Breast Cancer: Selective Estrogen Enzyme Modulator Actions

Peripheral neuropathy as a critical limiting factor in anticancer treatment

Cisplatin-induced PN as a paradigm of CIPN

VPA in CDDP-induced PN: two birds with one stone?

Other histone hyper-acetylating strategies: Acetyl-L-carnitine

Targeting Cancer and Neuropathy with Histone Deacetylase Inhibitors

Bentham Science Publishers

"Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in anti-cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. Each volume is devoted to the major advances in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
The eighth volume of the series features chapters covering the following topics:
- T cells in gastrointestinal cancers
- The pharmacology of adjudin – a male contraceptive with anti-cancer properties
- Manipulating the tumor microenvironment
- Treatment of hepatocellular carcinoma
- Gold-based compounds as potential anti-cancer drug candidates
- Oral nanostructure drug delivery for anti-cancer treatment"


Frontiers in Anti-Cancer Drug Discovery: Volume 8

Atta-ur-Rahman

Dr. M. lqbal Choudhary 

Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. Volume 9 features reviews on these topics: 
 
 
 
·         Dietary Strategy for Cancer Therapy - Amino Acid Restrictions and Beyond
 
·         The Revolutionary Potential of Noble Metal Nanoparticles as Anti-Cancer Agents: State-of-the-Art Applications and Future Perspectives
 
·         Algal Polysaccharides as Promising Anticancer Agents
 
·         Cardiotoxicity Caused by Doxorubicin and Trastuzumab: Current Understanding for Future Preventive Strategies
 
·         Emodin: Anticancer Agent 
 
 
 
Readership
 
Pharmaceutical Scientists, Medicinal Chemists, Clinical Oncologists, Researchers in Pre-clinical studies and clinical trials.

Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 9

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
This volume includes reviews on the following topics: 
-the role of microvesicles and exosomes in mesenchymal stem cell (MSCs) in treating diseases while overcoming side effects
-alternative models for understanding cancer stem cell biology
-stem cells treatments for orthopaedic injury and endocrine disorders
-wound healing biomaterials
-theoretical models of hematopoietic cell dynamics (with implications for bone marrow transplants)"


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 8

Shazia Anjum

"Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bioactive natural products that have huge potential as drugs. Each volume presents comprehensive chapters contributed by eminent scientists. The volumes focus on drug candidates which are in the later stages of drug development and are being evaluated in clinical trials. The series, therefore, highlights the importance of natural products in our lives.
 
The second volume covers the following topics:
 
- A review of recent patents and natural products in clinical trials to treat schistosomiasis
 
- Natural products: the new intervention regimen for metabolic disorders
 
- Fluorine-containing drugs and drug candidates derived from natural products
 
- Natural products for the management of cardiovascular diseases 
 
- Implication of natural compounds for the prevention of ocular diseases"


Natural Products in Clinical Trials: Volume 2

"Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery. Eminent scientists have contributed chapters focused on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, and structure-activity relationships. This book series should prove to be of interest to all pharmaceutical scientists who are involved in research in drug design and discovery and who wish to keep abreast of rapid and important developments in the field.
 
The tenth volume of this series brings together reviews covering topics related to the treatment of neoplasms, systems biology, respiratory diseases among others.
 
Topics included in this volume are:
 
- Recombinant Protein Production: from Bench to Biopharming
- Plant Virus Nanoparticles and Virus like Particles (VLPs): Applications in Medicine
- MAO Inhibitory Activity Of 4, 5-Dihydro-1 HPyrazole Derivatives: A Platform To Design Novel Antidepressants
- Flavonoids Antagonize Effects of Alcohol in Cultured Hippocampal Neurons: A Drug Discovery Study
- Hybrid Smart Materials for Topical Drug Delivery: Application of Scaffolds"


Frontiers in Drug Design & Discovery: Volume 10

"Frontiers in Clinical Drug Research – Diabetes and Obesity is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research.
 
The fourth volume of this series features 7 chapters:
 
-Pharmacologic Obesity Treatment
 
-Interplay Between Bile Acid and GLP-1 Receptor Agonist Signaling Informs the Design of Drugs to Combat Obesity and its Metabolic Complications
 
-Sodium–Glucose Co-Transporters Inhibitors for Type 2 Diabetes Mellitus
 
-The Effects of Traditional Chinese Medicine on Inflammatory Cytokines in Diabetic Nephropathy
 
-Through the Perspective of Histology – The Alzheimer’s Disease Promotion by Obesity and Glucose Metabolism: Type 3 Diabetes
 
-Pharmacological Mechanism of PPARγ Ratio in Diabetes and Obesity
 
-Hydrogen Sulfide and Carbohydrate Metabolism"


Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 4

Frontiers in Clinical Drug Research - Anti-Cancer Agents is abook series intended for pharmaceutical scientists, postgraduate students andresearchers seeking updated and critical information for developing clinicaltrials and devising research plans in anti-cancer research. Reviews in eachvolume are written by experts in medical oncology and clinical trials researchand compile the latest information available on special topics of interest tooncology and pharmaceutical chemistry researchers. The sixth volume of the book features reviews on these topics: · Immunomodulating Agents in The Treatment ofAcute Myeloid Leukemia · Potential Natural Products for Prostate CancerManagement· Inhibition of Key Protein-Protein Interactions bySmall Molecules for Cancer Drug Design· Efficacy of Hepatic Arterial InfusionChemotherapy (HAIC) For Advanced Hepatocellular Carcinoma· Targeting Cancer Stem Cells: Implications inHealth and Disease


Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 6

"Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research.
The fourth volume of this series features 5 chapters that cover these topics: 
- Design and Synthesis of HIV-1 Protease Inhibitors
- Potential Magnetic Nanotherapeutics for Management of neuroAIDS
- Syntheses of FDA Approved Integrase Inhibitor HIV Drugs and Improved Manufacturing using Flow Processing
- The Development and Clinical Progress on Chemokine Receptor-Based HIV Entry Inhibitors
- Sexually Transmitted Co-infections in Persons Living with HIV"


Frontiers in Clinical Drug Research - HIV: Volume 4

"Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.
 
This volume presents the following reviews:
Recent Progress on Asymmetric Synthesis of Chiral Flavanones, Chromanones, and Chromenes
Supramolecular Chemistry of Modified Amino Acids and Short Peptides
The Use of Nanocatalysts in the Synthesis of Heterocycles: A Contemporary Approach
Synthesis and Applications of 1,2,3-Triazoles
Ring C–H Functionalization of Aromatic N-Oxides 
 "


Advances in Organic Synthesis: Volume 12

Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field. This volume presents the following chapters:- “On Water” And “In Water” Strategies for Heterocyclic Transformations- Ionic Liquid Based Polyoxometalates as Functionalized Organic-Inorganic Hybrid Materials for Catalytic Organic Reactions- Recent Advances in the Synthesis and Bio-Applications of some Oxygen and Sulphur Containing Seven Membered Heterocyclic Compounds- Application of Nitriles on the Synthesis of 5-Membered Azaheterocycles: An Update from 2014 To 2020- The Role of Carbon-Based Solid Acid Catalysts in Organic Synthesis


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Advances in Cancer Drug Targets: Volume 1

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Atta-ur-Rahman

Frontiers in Anti-Cancer Drug Discovery: Volume 8

Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 9

Frontiers in Stem Cell and Regenerative Medicine Research: Volume 8

Natural Products in Clinical Trials: Volume 2

Frontiers in Drug Design & Discovery: Volume 10

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 4

Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 6

Frontiers in Clinical Drug Research - HIV: Volume 4

Advances in Organic Synthesis: Volume 12

Advances in Organic Synthesis: Volume 14

Atta-ur-Rahman