"Natural products continue to play a key role in drug development. A recent analysis of the drug market in the developed world revealed that 40% of total clinically approved drugs were either unmodified natural products or their semi-synthetic derivatives. This book series focuses on reviews of exciting new bioactive natural products that have huge potential as drugs. It highlights the everlasting importance of natural products in our lives. Each volume presents comprehensive reviews in cutting edge fields contributed by eminent scientists.
The first volume covers the following topics:
bioactive compounds from marine invertebrates
natural product derived drugs for immunological and inflammatory diseases
clinical trials of curcumin, camptothecin, astaxanthin, and biochanin
antibacterial and antifungal drugs from natural sources
natural products as anti-HIV medicines
 "


Natural Products in Clinical Trials: Volume 1

End User License Agreement (for non-institutional, personal use)

Clinical Trials for Deriving Bioactive Compounds from Marine Invertebrates

Natural Product derived anti-inflammatory drugs in clinical trials

Natural product derived immunological drugs in clinical trial

Immunosuppressive Compounds from Marine Sponges

Natural Product Derived Drugs for Immunological and Inflammatory Diseases

Clinical Trials of Curcumin, Camptothecin, Astaxanthin and Biochanin

MARKETED ANTIBACTERIALS FROM NATURAL SOURCE

MARKETED ANTIFUNGALS FROM NATURAL SOURCES

CURRENT ANTIBACTERIAL AGENTS IN CLINICAL DEVELOPMENT (PHASE 1 TO 4) – FOCUS ON LAST 10 YEARS

CURRENT ANTI-FUNGAL AGENTS IN CLINICAL DEVELOPMENT (PHASE 1 TO 4) – FOCUS ON LAST 10 YEARS

Antibacterial and Antifungal Drugs from Natural Source: A Review of Clinical Development

Anti-HIV Drug Discovery Struggle: From Natural Products to Drug Prototypes

Bentham Science Publishers

"Frontiers in Clinical Drug Research – Central Nervous System presents the latest researches and clinical studies on the central nervous system (CNS). It covers a range of topics such as the development and pathophysiology of the brain and spinal cord, physiological sites of drug action in the CNS and clinical findings on drugs used to treat CNS defects due to injury or impaired development. In addition to clinical research on humans, the book also highlights other avenues of CNS medicine and research such as pain medicine, stem cell research, pharmacology, toxicology and translational models in animals.   
The second volume of the series features chapters on the following topics: 
- Nucleic acids as drugs for neurodegenerative diseases
- Cellular Cysteine Network (CYSTEINET):
- Non-motor Symptoms in Parkinson’s Disease and drug therapies
- Multi-modal pharmacological treatments for major depressive disorder"


Frontiers in Clinical Drug Research - Central Nervous System: Volume 2

Atta-ur-Rahman

Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The sixth volume of this series features 6 reviews which are informative guides to therapy and drug administration in diabetes and metabolic syndrome, for both the medical specialist and the pharmacologist. - The failing heart in diabetes with special emphasis on prevention- Flavonoids as prominent anti-diabetic agents- Chemosensor in glucose monitoring, advances and challenges - Synergistic drugs and polyherbal formulations for obesity: current status and future prospectives- Urge for herbal anti-diabetic medicines towards clinical and therapeutic implications- Curcuma longa as a dietary supplement and medication for diabetes mellitus: evidence from experimental studies


Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 6

Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.
Volume nine of the series brings together 7 reviews on a variety of natural products and sources along with a chapter on the basics of investigating antioxidant activity.
Propolis and its key chemical constituents: a promising natural product in therapeutic applications
Investigation of the effects of using omega-3 fatty acids on egg quality in functional egg production 
Quercetin, a flavonoid with remarkable anticancer activity 
Swertiamarin for the treatment of metabolic syndrome
Overview of traditional uses, phytochemistry and pharmacology of Peganum harmala l. 
Investigation of measurement methods of antioxidant activity and involved mechanisms
Recent progress on natural and synthetic flavanone and its derivatives
Role of virgin coconut oil as a multiple health promoting function oil

Frontiers in Natural Product Chemistry: Volume 9

"Frontiers in CNS Drug Discovery is a book series devoted to publishing reviews which highlight the latest advances in drug design and discovery for disorders of the central nervous system (CNS). Eminent scientists write contributions on all areas of CNS drug design and drug discovery, including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series is essential reading for all pharmaceutical scientists involved in CNS drug design and discovery who wish to keep abreast of rapid and important developments in the field.
 
The third volume of this series brings reviews on brain tumor treatment, neurodegeneration, hyperalgesia, cholinesterase inhibition and much more."


Frontiers in CNS Drug Discovery: Volume 3

"Recent Advances in Analytical Techniques is a series of updates in techniques used in chemical analysis. Each volume presents a selection of chapters that explain different analytical techniques and their use in applied research. Readers will find updated information about developments in analytical methods such as chromatography, electrochemistry, optical sensor arrays for pharmaceutical and biomedical analysis. 
The third volume of the series features seven reviews on a variety of techniques: 
 
Chiral Analysis of Methamphetamine and Related Controlled Substances in Forensic Science
Low-cost feedstocks for biofuels and high value added products production: Using multi-parameter flow cytometry as a tool to enhance the process efficiency
Recent Trends in the Application of Ionic Liquids for Micro Extraction Techniques 
Electrospun Nanofibers: Functional and Attractive Materials for the Sensing and Separation Approaches in Analytical Chemistry 
Neutron Activation Analysis: An Overview
Non-commercial Polysaccharides-based Chiral Selectors in Enantioselective Chromatography 
Ru(II)-polypyridyl Complexes as Potential Sensing Agents for Cations and Anions 
 "


Recent Advances in Analytical Techniques: Volume 3

Sibel A. Ozkan

"Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.
The fourth volume of the series features several reviews focusing on NMR spectroscopic techniques in food sciences. Readers will find references on methods used to test food quality, food color analysis, the role of Tannins in wine taste as well as NMR studies on lipid oxidation and large protein complexes."


Applications in Food Sciences

Dr. M. lqbal Choudhary 

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The seventh volume of this series features reviews on roles of mesenchymal stem cells and biomaterials in cartilage regeneration in vivo, liver regeneration, cardiogenesis and magnetic nanoparticles for regenerative therapy."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 7

Shazia Anjum

"Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spies have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are common part of regional diets and folk medicine.
 
 
 
The first volume of this series features the following reviews:
 
1.       Saffron: The Golden Spice
 
2.       The Effect of Crocus sativous (Saffron) on Respiratory System, Traditional and Experimental Evidences
 
3.       Nutraceutical Activities of Turmeric (Curcuma longa) and its Bioactive Constituent Curcumin
 
4.       Antibacterial and Anticancer Activities of Turmeric and its Active Ingredient Curcumin, and Mechanism of Action
 
5.       Strategies for Enhancement of Bioavailability and Bioactivity of Curcumin
 
6.       Effect of Curcumin on the Diversity of Gut Microbiota
 
7.       Turmeric and Inflammatory Diseases: An Overview of Clinical Evidence
 
8.       Pre-Clinical/Animal Studies Conducted on Turmeric and Curcumin and Their Formulations"


Science of Spices and Culinary Herbs - Latest Laboratory, Pre-clinical, and Clinical Studies

SAMMER YOUSUF

"Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD), a disease that causes dementia, or loss of brain function. This disease affects parts of the brain that affect memory, thought, and language. Chapters in each volume focus on drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.
 
Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in the field of Alzheimer’s disease research.
 
The seventh volume of this series features chapters covering critical discussions on AD biochemistry and new therapies. The reviews in this volume include:
- Deep Brain Stimulation in the Treatment of Alzheimer's disease
- ASS234: A New and Promising Anti-Alzheimer Agent
- Recent Advances in Alzheimer's Drug Discovery Research
- Alzheimer’s Disease and Proteasome: The Therapeutic Development and Management
- Alzheimer´s Disease: Fundamental Concepts, Novel Findings and Therapeutics Outcomes Coming from the Ca2+/cAMP Signalling Interaction
- Alzheimer's Disease: An Approach for Non-Pharmacological Therapies
- Past and Present Drug Development for Alzheimer's Disease.
 "

Frontiers in Clinical Drug Research - Alzheimer Disorders: Volume 7

"Frontiers in Natural Product Chemistry is a book series devoted to publishing monographs that highlight important advances in natural product chemistry. The series covers all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.
 
 
 
The sixth volume of the series brings five reviews covering these topics:
 
 
 
- Plant protein hydrolyzates from underutilized agricultural and agroindustrial sources: production, characterization and bioactive properties
 
- New developments in the quinolone class of antibacterial drugs
 
- Structure of fine starch prepared via a compressed hot water process
 
- Major metabolites of certain marketed plant alkaloids
 
- Natural products in cancer chemoprevention and chemotherapy"


Frontiers in Natural Product Chemistry: Volume 6

"Frontiers in Natural Product Chemistry is a book series devoted to important advances in natural product chemistry. The series features volumes that cover all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.
Volume 11 of the series brings together 5 reviews:
Medicinal importance of turmeric (curcuma longa) and its natural products
Novel natural compounds for hepatocellular carcinoma treatment
Herbal drug substitution (abhava-pratinidhi dravya): a key to stopping economic adulteration of botanical ingredients
Synthetic and natural agents as bacterial biofilm inhibitors
Quercetin chemistry, structural modifications, SAR studies and therapeutic applications: an update"


Frontiers in Natural Product Chemistry: Volume 11

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The fifth volume of this series features reviews on vascular regeneration, neuronal tissue grafting in animal CNS disease models, template mediated biomineralization in bones, corneal endothelium differentiation and stem cell uses for managing hepatocellular carcinoma."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 5

"Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bioactive natural products that have huge potential as drugs. Each volume presents comprehensive chapters contributed by eminent scientists. The volumes focus on drug candidates which are in the later stages of drug development and are being evaluated in clinical trials. The series, therefore, highlights the importance of natural products in our lives.
 
The second volume covers the following topics:
 
- A review of recent patents and natural products in clinical trials to treat schistosomiasis
 
- Natural products: the new intervention regimen for metabolic disorders
 
- Fluorine-containing drugs and drug candidates derived from natural products
 
- Natural products for the management of cardiovascular diseases 
 
- Implication of natural compounds for the prevention of ocular diseases"


Natural Products in Clinical Trials: Volume 2

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 7

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
This volume includes reviews on the following topics: 
-the role of microvesicles and exosomes in mesenchymal stem cell (MSCs) in treating diseases while overcoming side effects
-alternative models for understanding cancer stem cell biology
-stem cells treatments for orthopaedic injury and endocrine disorders
-wound healing biomaterials
-theoretical models of hematopoietic cell dynamics (with implications for bone marrow transplants)"


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 8

"Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine.
 
This volume includes current literature on a variety of topics:
 
-the utility of exogenous and endogenous neural stem cells in spinal cord injury
 
-somatic cells for human induced pluripotent stem cells (iPSCs)
 
-reactive oxygen species (ROS) mediated cellular signaling for stem cell differentiation
 
-the therapeutic potential of microRNAs in cardiac diseases
 
-stem cell therapy for the treatment of malaria"


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 9

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The sixth volume of this series features reviews on roles of mesenchymal stem cells in cartilage regeneration and bone regeneration, liver regeneration, cardiogenesis, cardiomyocyte differentiation, and regenerative therapy for neurodegenerative disorders."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 6

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The second volume of this series features reviews on several key topics in this field including cardiac regeneration strategies, induced pluripotent stem cell therapeutics, stem cell therapy for peripheral nerve and cutaneous injuries, dental tissue regeneration, the potential of stem cell differentiation into ovarian cells and much more."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 2

"Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research brings updates on multidisciplinary topics relevant to stem cell research and their application in regenerative medicine. The series is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine.
 
 
 
Volume 11 includes 5 chapters on these topics:
 
 
 
- The use of embryology in clinical practice
 
- Molecular regulation and signaling transduction in human tissue development
 
- Cell differentiation on hydrogels and its application in regenerative medicine
 
- Stem cell therapy for sepsis
 
- Tumorigenicity assessments for stem cell-derived therapeutic products
 
 
 
Readership
 
Pharmaceutical scientists, biomedical researchers, stem cell biologists, pre-clinical and clinical researchers, life science, researchers, healthcare professionals in regenerative medicine"


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Natural Products in Clinical Trials: Volume 1

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About the authors

Atta-ur-Rahman

Frontiers in Clinical Drug Research - Central Nervous System: Volume 2

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 6

Frontiers in Natural Product Chemistry: Volume 9

Frontiers in CNS Drug Discovery: Volume 3

Recent Advances in Analytical Techniques: Volume 3

Applications in Food Sciences

Frontiers in Stem Cell and Regenerative Medicine Research: Volume 7

Science of Spices and Culinary Herbs - Latest Laboratory, Pre-clinical, and Clinical Studies

Frontiers in Clinical Drug Research - Alzheimer Disorders: Volume 7

Frontiers in Natural Product Chemistry: Volume 6

Atta-ur-Rahman

Shazia Anjum

Shazia Anjum