Advances in Cancer Drug Targets is an e-book series that brings together recent expert reviews published on the subject with a focus on strategies for synthesizing and isolating organic compounds and elucidating the structure and nature of DNA. The reference work serves to give readers a brief yet comprehensive glance at current theory and practice behind employing chemical compounds for tackling tumor suppression, DNA site specific drug targeting and the inhibition of enzymes involved in growth control pathways. The reviews presented in this series are written by experts in pharmaceutical sciences and molecular biology. These reviews have been carefully selected to present development of new approaches to anti-cancer therapy and anti-cancer drug development. This e-book volume will be of special interest to molecular biologists and pharmaceutical scientists.


Advances in Cancer Drug Targets: Volume 1

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The PIK3CA Gene as a Mutated Target for Cancer Therapy

AKT signaling is activated by VEGF and ANGiopoietins

Heavy metals regulate VEGF and HIF-1α expression via AKT pathway

AKT is the common target inhibited by different natural PRODUCTS with potential chemoprevention effects

Therapeutic perspectives for targeting AKT and mTOR

Inhibitors of Cyclin Dependent Kinases: Useful Targets for Cancer Treatment (An Update)

C-FILP AND THE DEATH RECEPTOR APOPTOSIS PATHWAY

TRANSCRIPTION AND TRANSLATION REGULATION OF C-FILP

C-FILP VARIANTS AS TARGETS FOR CANCER THERAPY

Cellular FLICE-Like Inhibitory Protein (C-FILP ): A Key Anti-Apoptotic Factor and a Target for Cancer Therapy

PIN1: A UNIQUE CANCER TARGET ACTING ON NUMEROUS CANCER-DRIVING PATHWAYS

Pin1: A Promising Novel Diagnostic and Therapeutic Target that Acts on Numerous Cancer-Driving Pathways

INDUCTION OF ANTICANCER IMMUNE REACTIVITY: IMMUNOREGULATORY DENDRITIC CELLS ORCHESTRATE THE DEVELOPMENT OF ANTI-CANCER T CELL REACTIVITY

INDUCTION OF ANTI-CANCER T CELL REACTIVITY BY DENDRITIC CELL VACCINES

THE EFFECTOR PHASE OF ANTICANCER IMMUNITY

IMMUNOSUPPRESSIVE EFFECTS OF CHEMOTHERAPY

REGULATORY T CELLS, TH17 T CELLS AND MESENCHYMAL STROMAL/STEM CELLS - KEY REGULATORS OF ANTICANCER IMMUNE REACTIVITY

ALLOGENEIC STEM CELL TRANSPLANTATION - AN ESTABLISHED COMBINATION OF PROAPOPTOTIC CHEMOTHERAPY AND IMMUNOTHERAPY

Anticancer Immunotherapy in Combination with Proapoptotic Therapy - Possible Therapeutic Strategies for Enhancement of Anticancer Immune Reactivity in Autologous Immunocompetent Cells and After Allogeneic Stem Cell Transplantation

INTRACRINOLOGY OF ESTROGEN DEPENDENT HUMAN BREAST CARCINOMA

MELATONIN AS A SELECTIVE ESTROGEN ENZYME MODULATOR

Melatonin and Breast Cancer: Selective Estrogen Enzyme Modulator Actions

Peripheral neuropathy as a critical limiting factor in anticancer treatment

Cisplatin-induced PN as a paradigm of CIPN

VPA in CDDP-induced PN: two birds with one stone?

Other histone hyper-acetylating strategies: Acetyl-L-carnitine

Targeting Cancer and Neuropathy with Histone Deacetylase Inhibitors

Bentham Science Publishers

"Frontiers in Clinical Drug Research – Diabetes and Obesity is an eBook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research.
 
The fourth volume of this series features 7 chapters:
 
-Pharmacologic Obesity Treatment
 
-Interplay Between Bile Acid and GLP-1 Receptor Agonist Signaling Informs the Design of Drugs to Combat Obesity and its Metabolic Complications
 
-Sodium–Glucose Co-Transporters Inhibitors for Type 2 Diabetes Mellitus
 
-The Effects of Traditional Chinese Medicine on Inflammatory Cytokines in Diabetic Nephropathy
 
-Through the Perspective of Histology – The Alzheimer’s Disease Promotion by Obesity and Glucose Metabolism: Type 3 Diabetes
 
-Pharmacological Mechanism of PPARγ Ratio in Diabetes and Obesity
 
-Hydrogen Sulfide and Carbohydrate Metabolism"


Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 4

Atta-ur-Rahman

Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology.
 
 
 
The fifth volume of this series features 7 reviews with a focus on thalassemia treatment and preeclampsia among other topics.
 
 
 
- Recent advances in the diagnosis and management of pulmonary embolism
 
- An evidence-based approach to treatment with iron chelators in transfusion- dependent thalassemia patients: present trends and future scenario
 
- Current and future treatments of iron overload in thalassemia patients
 
- Preeclampsia: biological and clinical aspects
 
- Haematological modulations by fixed dose combination (FDC) of tramadol hydrochloride/paracetamol (THP)
 
- Possible use of eculizumab in critically ill patients infected with covid-19 role of complement c5, neutrophils, and nets in the induction DIC, sepsis, and MOF hematological markers
 
- Emerging diagnostic and therapeutic targets in preeclampsia

Frontiers in Clinical Drug Research - Hematology: Volume 5

"Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD), a disease that causes dementia, or loss of brain function. This disease affects parts of the brain that affect memory, thought, and language. Chapters in each volume focus on drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.
 
Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in the field of Alzheimer’s disease research.
 
The seventh volume of this series features chapters covering critical discussions on AD biochemistry and new therapies. The reviews in this volume include:
- Deep Brain Stimulation in the Treatment of Alzheimer's disease
- ASS234: A New and Promising Anti-Alzheimer Agent
- Recent Advances in Alzheimer's Drug Discovery Research
- Alzheimer’s Disease and Proteasome: The Therapeutic Development and Management
- Alzheimer´s Disease: Fundamental Concepts, Novel Findings and Therapeutics Outcomes Coming from the Ca2+/cAMP Signalling Interaction
- Alzheimer's Disease: An Approach for Non-Pharmacological Therapies
- Past and Present Drug Development for Alzheimer's Disease.
 "

Frontiers in Clinical Drug Research - Alzheimer Disorders: Volume 7

"Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research.
 
 
 
The fifth volume of this series features 5 reviews which are informative guides to therapy and drug administration in diabetes and metabolic syndrome, for both the medical specialist and the pharmacologist.
 
 
 
-Metabolic syndrome in schizophrenia
 
-Insulin therapy and foetoplacental endothelial dysfunction in gestational diabetes mellitus
 
-Insights on diabetes, oxidative stress and antioxidant therapeutic strategies
 
-Administration of nano drugs in the treatment of diabetes mellitus
 
-SGLT-2 inhibitors"


Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 5

"Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest and the most important advances in anti-cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. Each volume is devoted to the major advances in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
The eighth volume of the series features chapters covering the following topics:
- T cells in gastrointestinal cancers
- The pharmacology of adjudin – a male contraceptive with anti-cancer properties
- Manipulating the tumor microenvironment
- Treatment of hepatocellular carcinoma
- Gold-based compounds as potential anti-cancer drug candidates
- Oral nanostructure drug delivery for anti-cancer treatment"


Frontiers in Anti-Cancer Drug Discovery: Volume 8

Dr. M. lqbal Choudhary 

"Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture.
The third volume of this book series features six reviews covering structure-property relationship of polyphenols, NMR spectroscopy in breast cancer diagnosis, NMR methods in drug discovery and formulation, protein confirmation analysis using Fluorine NMR and NMR studies enaminones."


Applications of NMR Spectroscopy: Volume 3

"Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. It presents comprehensive articles written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations. Contributions are written by eminent scientists and each volume is edited by an authority in the field. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.
 
This volume presents the following reviews:
Catalytic Tandem Reactions Triggered by the Introduction of a Carbonyl Function
Synthetic Applications of Bifunctional Knölker Type Iron Complexes as (De)hydrogenation Catalysts
Superelectrophilic Activation of Alkynes, Alkenes, and Allenes
Chitosan and its Derivatives: Synthesis Strategy and Applications
Synthesis of N-Containing Heterocycles via Hypervalent Iodine(III)-Mediated Intramolecular Oxidative Cyclization
Advancements in Ionic Liquids for the Formation of Morita Baylis-Hillman Adducts
 "


Advances in Organic Synthesis: Volume 8

"Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.
 
Contents of this volume include these 6 reviews:
 
- Multicomponent synthesis of heterocycles by microwave irradiation
- Stereoselective procedures for the synthesis of olefines
- Advanced microwave assisted organic synthesis method in organic chemistry
- Five and six-membered n-heterocycle rings from diaminomaleonitrile
- Peptidomimetics: current and future perspectives on hiv protease inhibitors
- A review on synthesis, chemistry, and medicinal properties of benzothiazines and their related scaffolds"


Advances in Organic Synthesis: Volume 17

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The fifth volume of this series features reviews on vascular regeneration, neuronal tissue grafting in animal CNS disease models, template mediated biomineralization in bones, corneal endothelium differentiation and stem cell uses for managing hepatocellular carcinoma."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 5

Shazia Anjum

"Frontiers in Clinical Drug Research - Anti-Cancer Agents is an eBook series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology researchers.
The third volume of the eBook series begins with a detailed review of the molecular biology of inhibitors that target EGF-family receptors. This review is divided into two parts that covers extracellular and intracellular molecules. Other reviews cover targeted therapies for cancers such as melanoma, follicular lymphoma and topics such as cancer immunotherapy, apoptosis targeting and the Warburg Effect."


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Advances in Cancer Drug Targets: Volume 1

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Atta-ur-Rahman

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 4

Frontiers in Clinical Drug Research - Hematology: Volume 5

Frontiers in Clinical Drug Research - Alzheimer Disorders: Volume 7

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 5

Frontiers in Anti-Cancer Drug Discovery: Volume 8

Applications of NMR Spectroscopy: Volume 3

Advances in Organic Synthesis: Volume 8

Advances in Organic Synthesis: Volume 17

Frontiers in Stem Cell and Regenerative Medicine Research: Volume 5

Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 3

Atta-ur-Rahman