"Natural products continue to play a key role in drug development. A recent analysis of the drug market in the developed world revealed that 40% of total clinically approved drugs were either unmodified natural products or their semi-synthetic derivatives. This book series focuses on reviews of exciting new bioactive natural products that have huge potential as drugs. It highlights the everlasting importance of natural products in our lives. Each volume presents comprehensive reviews in cutting edge fields contributed by eminent scientists.
The first volume covers the following topics:
bioactive compounds from marine invertebrates
natural product derived drugs for immunological and inflammatory diseases
clinical trials of curcumin, camptothecin, astaxanthin, and biochanin
antibacterial and antifungal drugs from natural sources
natural products as anti-HIV medicines
 "


Natural Products in Clinical Trials: Volume 1

End User License Agreement (for non-institutional, personal use)

Clinical Trials for Deriving Bioactive Compounds from Marine Invertebrates

Natural Product derived anti-inflammatory drugs in clinical trials

Natural product derived immunological drugs in clinical trial

Immunosuppressive Compounds from Marine Sponges

Natural Product Derived Drugs for Immunological and Inflammatory Diseases

Clinical Trials of Curcumin, Camptothecin, Astaxanthin and Biochanin

MARKETED ANTIBACTERIALS FROM NATURAL SOURCE

MARKETED ANTIFUNGALS FROM NATURAL SOURCES

CURRENT ANTIBACTERIAL AGENTS IN CLINICAL DEVELOPMENT (PHASE 1 TO 4) – FOCUS ON LAST 10 YEARS

CURRENT ANTI-FUNGAL AGENTS IN CLINICAL DEVELOPMENT (PHASE 1 TO 4) – FOCUS ON LAST 10 YEARS

Antibacterial and Antifungal Drugs from Natural Source: A Review of Clinical Development

Anti-HIV Drug Discovery Struggle: From Natural Products to Drug Prototypes

Bentham Science Publishers

"Frontiers in Medicinal Chemistry is an Ebook series devoted to reviews on research topics relevant to medicinal chemistry and allied disciplines. Frontiers in Medicinal Chemistry covers developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships.  This Ebook series is essential for any medicinal chemist who wishes to be updated on the latest and the most important advances in the field.
This volume features reviews on the following topics:
Purinergic receptors and pain
Cytochrome c – cardiolipin interactions in cells
Dipeptidyl peptidase-4 (CD26) functions and inhibition
Peptides regulating angiogenesis
Application of melanotropin ligands for the treatment of obesity and related disorders
Targeted drugs in the field of nanomedicine"


Frontiers in Medicinal Chemistry: Volume 9

Atta-ur-Rahman

"Topics in Anti-Cancer Research covers new developments in the field of cancer diagnosis and drug therapy. Novel drugs as anticancer agents include natural and synthetic phenazirines and other anti-cancer compounds. The series also covers information on the current understanding of the pathology and molecular biology of specific neoplasms.
 
The diversity of research topics published in this book series give broad and valuable perspectives for cancer researchers, clinicians, cancer professionals aiming to develop novel anti-cancer targets and patents for the treatment of various cancers.
 
The topics covered in this volume are:
- Peptides can play a major role in combating cancer diseases
- Studying of the CLL after treatment using fractal parameter of neoplastic lymphocytes detection (ΛNLD)
- Mechanistic insight of rhenium-based compounds as anti- cancer agents
- Targeting cancer-specific inflammatory components in cancer therapeutics
- Marine natural products as a source of novel anticancer agents: a treasure from the ocean
- PDX clinical trial design in anti-cancer research"


Topics in Anti-Cancer Research: Volume 10

"Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.
 
This volume presents the following reviews:
Recent Progress on Asymmetric Synthesis of Chiral Flavanones, Chromanones, and Chromenes
Supramolecular Chemistry of Modified Amino Acids and Short Peptides
The Use of Nanocatalysts in the Synthesis of Heterocycles: A Contemporary Approach
Synthesis and Applications of 1,2,3-Triazoles
Ring C–H Functionalization of Aromatic N-Oxides 
 "


Advances in Organic Synthesis: Volume 11

"Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology.
 
 
 
The ninth volume of this series features reviews that cover the following topics related to the treatment of a different CNS disorders, related diseases and basic neuropharmacology research:
 
 
 
- Integrating imaging and microdialysis into systems neuropharmacology
 
- Depression heterogeneity and the potential of a transdiagnostic and dimensional approach to identify biologically relevant phenotypes
 
- CAR-T cells in brain tumors and autoimmune diseases – from basics to the clinic
 
- Revaluation of thyrotropin-releasing hormone and its mimetics as candidates for treating a wide range of neurological and psychiatric disorders
 
- Natural BACE1 inhibitors: promising drugs for the management of Alzheimer’s disease
 
- The possibilities of safe lithium therapy in the treatment of neurological and psychoemotional disorders
 
- Pharmacotherapy of multiple sclerosis and treatment strategies"


Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9

 Zareen Amtul

"Frontiers in Medicinal Chemistry is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. Frontiers in Medicinal Chemistry covers all the areas of medicinal chemistry, including developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships.  This Ebook series is essential for any medicinal chemist who wishes to be kept informed and up-to-date with the latest and the most important advances.
This volume features reviews on the following topics:
ADME optimization and toxicity assessment in drug discovery
Targeting oxidative stress mechanisms in vascular disease therapy
Diabetes therapy that targets endothelial function
… and more."


Frontiers in Medicinal Chemistry: Volume 8

"Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.
 
 
 
The eighth volume of this series presents comprehensive reviews of interest to readers interested in the treatment of inflammatory diseases, new antiviral agents and strategies, specific antiprotozoal drugs that work against leishmania and helminths,  and a study on potential agents against American foulbrood in honey bees. The 7 reviews included in this volume are:
 
- Monoclonal antibodies as therapeutic agents for inflammatory diseases
 
- Pharmacotherapy of emerging antiviral agents
 
- Antiviral activity of vitamin D and COVID-19: current understanding
 
- Anti-infectives to combat leishmaniasis
 
- Anthelmintic drug discovery: current situation and future perspectives
 
- Therapeutic targets for emerging Zika virus infection and vaccines in clinical trials
 
- Agro-industrial waste: new source of raw material for the control of American foulbrood in honey bees"


Frontiers in Clinical Drug Research - Anti Infectives: Volume 8

"Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology.
The fourth volume of this series features 5 reviews:
-TRP Channels: Potential Therapeutic Targets in Blood Disorders
-Hypercoagulable States: Clinical Symptoms, Laboratory Markers and Management
-Advanced Applications of Gene Therapy in the Treatment of Hematologic Disorders
-Ferroptosis - Importance and Potential Effects in Hematological Malignancies
-Clinical Application of Liquid Biopsy in Solid Tumor HCC: Prognostic, Diagnostic and Therapy Monitoring Tool"


Frontiers in Clinical Drug Research - Hematology: Volume 4

"Recent Advances in Medicinal Chemistry is a book series focused on leading-edge research on developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The series presents highly cited contributions first published in the impact factor journal Mini-Reviews in Medicinal Chemistry. Contributors to this volume have updated their work with new experimental data and references following their initial research. Each volume highlights a number of important topics in current research in medicinal chemistry.
Selected chapters in this volume include:
- Characterization of Inorganic Nanomaterials as Therapeutic Vehicles
- HPLC and its Essential Role in the Analysis of Tricyclic Antidepressants in Biological Samples
- Tannins and Their Influence on Health
… And much more."


Recent Advances in Medicinal Chemistry: Volume 1

"This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.
Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.
The sixth volume of this series features 6 chapters that cover the following topics:
- Alternative anti-infective / anti-inflammatory therapeutic options for fighting Alzheimer’s disease
- Microbial peptides that combat microbial biofilms 
- Malaria and its treatment
- Tuberculosis drugs
… and much more."


Frontiers in Anti-Infective Drug Discovery: Volume 6

Dr. M. lqbal Choudhary 

"Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research.
 
 
 
The fifth volume of this series features 5 reviews which are informative guides to therapy and drug administration in diabetes and metabolic syndrome, for both the medical specialist and the pharmacologist.
 
 
 
-Metabolic syndrome in schizophrenia
 
-Insulin therapy and foetoplacental endothelial dysfunction in gestational diabetes mellitus
 
-Insights on diabetes, oxidative stress and antioxidant therapeutic strategies
 
-Administration of nano drugs in the treatment of diabetes mellitus
 
-SGLT-2 inhibitors"


Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 5

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
This volume includes reviews on the following topics: 
-the role of microvesicles and exosomes in mesenchymal stem cell (MSCs) in treating diseases while overcoming side effects
-alternative models for understanding cancer stem cell biology
-stem cells treatments for orthopaedic injury and endocrine disorders
-wound healing biomaterials
-theoretical models of hematopoietic cell dynamics (with implications for bone marrow transplants)"


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 8

Shazia Anjum

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The sixth volume of this series features reviews on roles of mesenchymal stem cells in cartilage regeneration and bone regeneration, liver regeneration, cardiogenesis, cardiomyocyte differentiation, and regenerative therapy for neurodegenerative disorders."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 6

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The second volume of this series features reviews on several key topics in this field including cardiac regeneration strategies, induced pluripotent stem cell therapeutics, stem cell therapy for peripheral nerve and cutaneous injuries, dental tissue regeneration, the potential of stem cell differentiation into ovarian cells and much more."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 2

"Advances in Organic Synthesis is a book series devoted to the latest advances in synthetic approaches towards challenging structures. The series presents comprehensive reviews written by eminent authorities on different synthetic approaches to selected target molecules and new methods developed to achieve specific synthetic transformations or optimal product yields. Advances in Organic Synthesis is essential for all organic chemists in academia and the industry who wish to keep abreast of rapid and important developments in the field.
 
 
 
Volume 18 presents 7 reviews focused on ionic materials, nanoparticles and nitrogen containing heterocycles in organic synthesis.
 
 
 
- Recent synthetic and biological advances in anti-cancer ferrocene-analogues and hybrids
 
- Synthesis of fused nitrogenated heterocycles: intramolecular povarov reaction
 
- Use of barbituric acid as a precursor for the synthesis of bioactive compound
 
- Ionic liquids as solvents and/or catalysts for organic synthesis
 
- Zinc oxide nanomaterials for biomedical applications
 
- Superhydrophobic polymeric nanocomposites coatings for effective corrosion protection
 
- Morphologies and properties of virgin and waste PP nanocomposites"


Advances in Organic Synthesis​: Volume 18

"Frontiers in Natural Product Chemistry is a book series devoted to important advances in natural product chemistry. The series features volumes that cover all aspects of research in the chemistry and biochemistry of naturally occurring compounds, including research on natural substances derived from plants, microbes and animals. Reviews of structure elucidation, biological activity, organic and experimental synthesis of natural products as well as developments of new methods are also included in the series.
Volume 11 of the series brings together 5 reviews:
Medicinal importance of turmeric (curcuma longa) and its natural products
Novel natural compounds for hepatocellular carcinoma treatment
Herbal drug substitution (abhava-pratinidhi dravya): a key to stopping economic adulteration of botanical ingredients
Synthetic and natural agents as bacterial biofilm inhibitors
Quercetin chemistry, structural modifications, SAR studies and therapeutic applications: an update"


Frontiers in Natural Product Chemistry: Volume 11

"Natural compounds continue to play a key role in drug development. Many clinically approved drugs are either unmodified natural products or their semi-synthetic derivatives. This book series presents reviews of exciting new bioactive natural products that have huge potential as drugs. Each volume presents comprehensive chapters contributed by eminent scientists. The volumes focus on drug candidates which are in the later stages of drug development and are being evaluated in clinical trials. The series, therefore, highlights the importance of natural products in our lives.
 
The second volume covers the following topics:
 
- A review of recent patents and natural products in clinical trials to treat schistosomiasis
 
- Natural products: the new intervention regimen for metabolic disorders
 
- Fluorine-containing drugs and drug candidates derived from natural products
 
- Natural products for the management of cardiovascular diseases 
 
- Implication of natural compounds for the prevention of ocular diseases"


Natural Products in Clinical Trials: Volume 2

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The seventh volume of this series features reviews on roles of mesenchymal stem cells and biomaterials in cartilage regeneration in vivo, liver regeneration, cardiogenesis and magnetic nanoparticles for regenerative therapy."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 7

Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The sixth volume of this series features 6 reviews which are informative guides to therapy and drug administration in diabetes and metabolic syndrome, for both the medical specialist and the pharmacologist. - The failing heart in diabetes with special emphasis on prevention- Flavonoids as prominent anti-diabetic agents- Chemosensor in glucose monitoring, advances and challenges - Synergistic drugs and polyherbal formulations for obesity: current status and future prospectives- Urge for herbal anti-diabetic medicines towards clinical and therapeutic implications- Curcuma longa as a dietary supplement and medication for diabetes mellitus: evidence from experimental studies


Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 7

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The fifth volume of this series features reviews on vascular regeneration, neuronal tissue grafting in animal CNS disease models, template mediated biomineralization in bones, corneal endothelium differentiation and stem cell uses for managing hepatocellular carcinoma."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 5

"Stem cell and regenerative medicine research is an important area of clinical research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer’s disease and retinal disorders, among others, may well be addressed employing stem cell therapies and tissue regeneration techniques. Frontiers in Stem Cell and Regenerative Medicine Research brings updates on multidisciplinary topics relevant to stem cell research and their application in regenerative medicine. The series is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine.
 
 
 
Volume 11 includes 5 chapters on these topics:
 
 
 
- The use of embryology in clinical practice
 
- Molecular regulation and signaling transduction in human tissue development
 
- Cell differentiation on hydrogels and its application in regenerative medicine
 
- Stem cell therapy for sepsis
 
- Tumorigenicity assessments for stem cell-derived therapeutic products
 
 
 
Readership
 
Pharmaceutical scientists, biomedical researchers, stem cell biologists, pre-clinical and clinical researchers, life science, researchers, healthcare professionals in regenerative medicine"


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Natural Products in Clinical Trials: Volume 1

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Atta-ur-Rahman

Frontiers in Medicinal Chemistry: Volume 9

Topics in Anti-Cancer Research: Volume 10

Advances in Organic Synthesis: Volume 11

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9

Frontiers in Medicinal Chemistry: Volume 8

Frontiers in Clinical Drug Research - Anti Infectives: Volume 8

Frontiers in Clinical Drug Research - Hematology: Volume 4

Recent Advances in Medicinal Chemistry: Volume 1

Frontiers in Anti-Infective Drug Discovery: Volume 6

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 5

Atta-ur-Rahman

Shazia Anjum

Shazia Anjum