Department of Pediatrics and Cell and Developmental Biology,Vanderbilt University Medical Center,Nashville,USA Dr. Baldwin’s research efforts have concentrated on delineating the molecular basis of vascular development in the mammalian embryo as an approach to understanding the etiology of congenital heart diseases. His laboratory efforts are based on the hypothesis that the developing vasculature provides important patterning information that directs subsequent cardiac and pulmonary morphogenetic events. Investigations have focused on two areas: 1) the role of endothelial cell adhesion molecules, particularly PECAM-1, in regulating vascular ontogeny and 2) the role of NFATc-1 in specification of endocardial development during early organogenesis. Department of Pediatrics and Cell and Developmental Biology,Vanderbilt University Medical Center,Nashville,USA Dr. Baldwin’s research efforts have concentrated on delineating the molecular basis of vascular development in the mammalian embryo as an approach to understanding the etiology of congenital heart diseases. His laboratory efforts are based on the hypothesis that the developing vasculature provides important patterning information that directs subsequent cardiac and pulmonary morphogenetic events. Investigations have focused on two areas: 1) the role of endothelial cell adhesion molecules, particularly PECAM-1, in regulating vascular ontogeny and 2) the role of NFATc-1 in specification of endocardial development during early organogenesis.