"Frontiers in Clinical Drug Research - Anti-Cancer Agents is an eBook series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology researchers.
The third volume of the eBook series begins with a detailed review of the molecular biology of inhibitors that target EGF-family receptors. This review is divided into two parts that covers extracellular and intracellular molecules. Other reviews cover targeted therapies for cancers such as melanoma, follicular lymphoma and topics such as cancer immunotherapy, apoptosis targeting and the Warburg Effect."


Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 3

End User License Agreement (for non-institutional, personal use)

2. LINKING THE EGFR WITH CANCER THERAPUTICS

4. BIOMARKERS PREDICTING SENSITIVITY AND RESISTANCE TO ANTI-EGFR THERAPIES - LIGANDS OF THE EGFR AS PREDICTORS OF RESPONSE TO ANTI-EGFR THERAPY

5. BIOMARKERS PREDICTING SENSITIVITY AND RESISTANCE TO ANTI-EGFR THERAPIES - ALTERATIONS IN ERBB RECEPTORS FAMILY MEMBERS

6. Alterations in Non-ErbB Receptor Family Members

Tumor Resistance Mechanisms to Inhibitors Targeting the Epidermal Growth Factor Receptor– Part I: Extracellular Molecules

2. INTRACELLULAR TRAFFICKING OF THE egfr AND RESISTANCE TO ANTI-eGFR Therapy

3. The ras/ref/mek/erk Signaling Pathway AND RESISTANCE TO ANTI-eGFR Therapy

4. The PI3-K Signaling Pathway AND RESISTANCE TO ANTI-eGFR Therapy

5. ANALYSIS OF SEVERAL BIOMARKERS IN COMBINATION AND RESISTANCE TO ANTI-eGFR Therapy

6. The JAK/STAT Signaling Pathway AND RESISTANCE TO ANTI-eGFR Therapy

Tumor Resistance Mechanisms to Inhibitors Targeting the Epidermal Growth Factor Receptor – Part II: Intracellular Molecules

Chemotherapeutic, Immunologic, and Molecularly Targeted Therapy for the Treatment of Advanced Melanoma

1. THERAPEUTICAL APPROACHES TO CANCER: FROM Chemotherapy to Targeted Therapies

3. THE WARBURG EFFECT: CURRENT PERSPECTIVE

4. CURRENT AND PAST EFFORTS AT TARGETING THE WARBURG EFFECT FOR CANCER THERAPY

Targeting the Warburg Effect for Cancer Therapy: A Long and Winding Road

3. Previous Considerations before Therapy

6. Novel and Emerging Pharmacological Agents

7. Innovative Immunotherapy Strategies for Treatment of FL

Immunotherapy Strategies in Follicular Lymphoma: Antibodies, Vaccines and Cells

Cancer Epigenetics AND Role in Carcinogenesis

Modulation of Metabolism by Epigenetic Dys-regulation

Epigenetic Regulation by the Availability of Co-substrates

Epigenetic Dysregulation Induced by Oncometabolites

Epigenetics and Cancer Cell Metabolism: Cross-talk and Therapeutic Opportunities

Apoptosis Targeting Therapeutics in Clinical Trials

Bentham Science Publishers

"The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, etc. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results.
Anti-angiogenesis Drug Discovery and Development provides an excellent compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. The feast of these reader-friendly reviews on topics of great scientific importance – many of which are considered significant medical breakthroughs, makes this series excellent reading both for the novice as well as for expert medicinal chemists and clinicians.
This volume brings together 5 reviews on the following topics:
- Retinal angiogenesis
- Effects of brief daily EMF therapy on tumor growths
- Evolution of the role of angiogenesis in cancer treatments over six decades
- Anti-angiogenesis drugs
- Anti-angiogenesis therapy for multiple sclerosis
- Update on the link between angiogenesis and portal hypertension"


Anti-Angiogenesis Drug Discovery and Development: Volume 4

Atta-ur-Rahman

Dr. M. lqbal Choudhary 

"Stem cell and regenerative medicine research is a hot area of research which promises to change the face of medicine as it will be practiced in the years to come. Challenges in the 21st century to combat diseases such as cancer, Alzheimer and related diseases may well be addressed employing stem cell therapies and tissue regeneration. Frontiers in Stem Cell and Regenerative Medicine Research is essential reading for researchers seeking updates in stem cell therapeutics and regenerative medicine. 
The sixth volume of this series features reviews on roles of mesenchymal stem cells in cartilage regeneration and bone regeneration, liver regeneration, cardiogenesis, cardiomyocyte differentiation, and regenerative therapy for neurodegenerative disorders."


Frontiers in Stem Cell and Regenerative Medicine Research: Volume 6

Shazia Anjum

"Frontiers in Anti-Cancer Drug Discovery is a book series devoted to publishing the latest advances in anti-cancer drug design and discovery. In each volume, eminent scientists contribute reviews relevant to all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The book series should prove to be of interest to all pharmaceutical scientists involved in research in anti-cancer drug design and discovery. The book series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.
 
The tenth volume of the series features chapters covering the following topics:
 
- Challenges in the Management of Hepatoblastoma
 
- The Emerging Role of Monocarboxylate Transporter-1 in Cancer
 
- In-vitro Anti-Proliferative Assays and Techniques Used in Pre-Clinical Anti-Cancer Drug Discovery
 
- Recent Advances in the Development of Mesoporous Anti-Cancer Drug Nanocarriers
 
- Polyphenols and Cancer
 
- Glioblastoma Multiforme
 
- Cutting Edge Targeting Strategies Utilizing Nanotechnology in Breast Cancer Therapy"


Frontiers in Anti-Cancer Drug Discovery: Volume 10

"Frontiers in Medicinal Chemistry is an Ebook series devoted to the review of areas of important topical interest to medicinal chemists and others in allied disciplines. Frontiers in Medicinal Chemistry covers all the areas of medicinal chemistry, including developments in rational drug design, bioorganic chemistry, high-throughput screening, combinatorial chemistry, compound diversity measurements, drug absorption, drug distribution, metabolism, new and emerging drug targets, natural products, pharmacogenomics, chemoinformatics, and structure-activity relationships.  This Ebook series is essential for any medicinal chemist who wishes to be kept informed and up-to-date with the latest and the most important advances.
This volume features reviews on the following topics:
ADME optimization and toxicity assessment in drug discovery
Targeting oxidative stress mechanisms in vascular disease therapy
Diabetes therapy that targets endothelial function
… and more."


Frontiers in Medicinal Chemistry: Volume 8

Advances in Organic Synthesis is abook series devoted to the latest advances in synthetic approaches towardschallenging structures. The series presents comprehensive reviews written byeminent authorities on different synthetic approaches to selected targetmolecules and new methods developed to achieve specific synthetictransformations or optimal product yields. Advances in Organic Synthesisis essential for all organic chemists in academia and the industry who wish tokeep abreast of rapid and important developments in the field. This volume presents the following reviews:Electroluminescent polymers - a review on synthesis from organic compoundsRemarkable advances in the asymmetric synthesis of biologically active natural compounds from the advent of chiral auxiliariesThe chemistry of ynamides and their application in organic synthesisCarbon-heteroatom bond formation for medium ring heterocyclesTin(ii) salts: versatile and efficient lewis acid catalysts in reactions to add value to the glycerol and terpenic alcohols(E)-n-methyl-1-(methylthio)-2-nitroethenamine (nmsm) as a versatile ambiphilic synthon in organic synthesis


Advances in Organic Synthesis: Volume 13

"Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research.
The fifth volume of this series features 5 chapters that cover these topics: 
- Clinical Eradication of Latent HIV Reservoirs: Where Are We Now?
- HIV-1 Genotypic Drug Resistance Testing and Next-Generation Sequencing
- Current and Promising Multiclass Drug Regimens and Long-Acting Formulation Drugs in HIV Therapy
- Role of Nanotechnology in HIV Diagnosis and Prognosis
- Preventive and Therapeutic Features of Combination Therapy for HIV"


Frontiers in Clinical Drug Research - HIV: Volume 5

"Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research.
The fourth volume of this series features 5 chapters that cover these topics: 
- Design and Synthesis of HIV-1 Protease Inhibitors
- Potential Magnetic Nanotherapeutics for Management of neuroAIDS
- Syntheses of FDA Approved Integrase Inhibitor HIV Drugs and Improved Manufacturing using Flow Processing
- The Development and Clinical Progress on Chemokine Receptor-Based HIV Entry Inhibitors
- Sexually Transmitted Co-infections in Persons Living with HIV"


Frontiers in Clinical Drug Research - HIV: Volume 4

"This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships.
Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field.
The seventh volume of this series features 7 chapters that cover the following topics:
- Gut micriobiota and gastrointestinal cancer
- Dengue virus infections
- Synergistic antibiotic drug interactions
- Molecular modeling of antibacterial drugs
- Nucleic acid aptamers as anti-infective agents
- Fungal multidrug resistance
- The role of hydrogen sulfide in infections 
"


Frontiers in Anti-Infective Drug Discovery: Volume 7

"Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology.
The fourth volume of this series features 5 reviews:
-TRP Channels: Potential Therapeutic Targets in Blood Disorders
-Hypercoagulable States: Clinical Symptoms, Laboratory Markers and Management
-Advanced Applications of Gene Therapy in the Treatment of Hematologic Disorders
-Ferroptosis - Importance and Potential Effects in Hematological Malignancies
-Clinical Application of Liquid Biopsy in Solid Tumor HCC: Prognostic, Diagnostic and Therapy Monitoring Tool"


Frontiers in Clinical Drug Research - Hematology: Volume 4

"Herbal Medicine: Back to the Future compiles expert reviews on the application of herbal medicines (including Ayurveda, Chinese traditional medicines and alternative therapies) to treat different ailments. The book series demonstrates the use of sophisticated methods to understand traditional medicine, while providing readers a glimpse into the future of herbal medicine.
 
 
 
This volume presents reviews of plant based therapies useful for treating different infectious diseases. The list of topics includes some niche reviews in this area including a review of the neem plant, the historical use of herbs in infectious disease therapy in Russia, and natural remedies from garlic, among other topics., The topics included in this volume are:
 
- Improving anti-microbial activity of allicin and carvacrol through stabilized analogs and nanotechnology
 
- Plant phenolics as an alternative source of antimicrobial compounds
 
- Herbal medicine in Russia’s history: the use of herbal medicine for infectious diseases in Russia’s history
 
- Azadirachta indica (neem) in various infectious diseases
 
- Contribution of novel delivery systems in the development of phytotherapeutics
 
 
 
This volume is essential reading for all researchers in the field of natural product chemistry and pharmacology. Medical professionals involved in internal medicine who seek to improve their knowledge about herbal medicine and alternative therapies for tropical and other infectious diseases will also benefit from the contents of the volume."


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Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 3

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About the authors

Atta-ur-Rahman

Anti-Angiogenesis Drug Discovery and Development: Volume 4

Frontiers in Stem Cell and Regenerative Medicine Research: Volume 6

Frontiers in Anti-Cancer Drug Discovery: Volume 10

Frontiers in Medicinal Chemistry: Volume 8

Advances in Organic Synthesis: Volume 13

Frontiers in Clinical Drug Research - HIV: Volume 5

Frontiers in Clinical Drug Research - HIV: Volume 4

Frontiers in Anti-Infective Drug Discovery: Volume 7

Frontiers in Clinical Drug Research - Hematology: Volume 4

Infectious Diseases

Atta-ur-Rahman