"Frontiers in Clinical Drug Research - Anti-Cancer Agents is an eBook series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology researchers.
The third volume of the eBook series begins with a detailed review of the molecular biology of inhibitors that target EGF-family receptors. This review is divided into two parts that covers extracellular and intracellular molecules. Other reviews cover targeted therapies for cancers such as melanoma, follicular lymphoma and topics such as cancer immunotherapy, apoptosis targeting and the Warburg Effect."


Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 3

End User License Agreement (for non-institutional, personal use)

2. LINKING THE EGFR WITH CANCER THERAPUTICS

4. BIOMARKERS PREDICTING SENSITIVITY AND RESISTANCE TO ANTI-EGFR THERAPIES - LIGANDS OF THE EGFR AS PREDICTORS OF RESPONSE TO ANTI-EGFR THERAPY

5. BIOMARKERS PREDICTING SENSITIVITY AND RESISTANCE TO ANTI-EGFR THERAPIES - ALTERATIONS IN ERBB RECEPTORS FAMILY MEMBERS

6. Alterations in Non-ErbB Receptor Family Members

Tumor Resistance Mechanisms to Inhibitors Targeting the Epidermal Growth Factor Receptor– Part I: Extracellular Molecules

2. INTRACELLULAR TRAFFICKING OF THE egfr AND RESISTANCE TO ANTI-eGFR Therapy

3. The ras/ref/mek/erk Signaling Pathway AND RESISTANCE TO ANTI-eGFR Therapy

4. The PI3-K Signaling Pathway AND RESISTANCE TO ANTI-eGFR Therapy

5. ANALYSIS OF SEVERAL BIOMARKERS IN COMBINATION AND RESISTANCE TO ANTI-eGFR Therapy

6. The JAK/STAT Signaling Pathway AND RESISTANCE TO ANTI-eGFR Therapy

Tumor Resistance Mechanisms to Inhibitors Targeting the Epidermal Growth Factor Receptor – Part II: Intracellular Molecules

Chemotherapeutic, Immunologic, and Molecularly Targeted Therapy for the Treatment of Advanced Melanoma

1. THERAPEUTICAL APPROACHES TO CANCER: FROM Chemotherapy to Targeted Therapies

3. THE WARBURG EFFECT: CURRENT PERSPECTIVE

4. CURRENT AND PAST EFFORTS AT TARGETING THE WARBURG EFFECT FOR CANCER THERAPY

Targeting the Warburg Effect for Cancer Therapy: A Long and Winding Road

3. Previous Considerations before Therapy

6. Novel and Emerging Pharmacological Agents

7. Innovative Immunotherapy Strategies for Treatment of FL

Immunotherapy Strategies in Follicular Lymphoma: Antibodies, Vaccines and Cells

Cancer Epigenetics AND Role in Carcinogenesis

Modulation of Metabolism by Epigenetic Dys-regulation

Epigenetic Regulation by the Availability of Co-substrates

Epigenetic Dysregulation Induced by Oncometabolites

Epigenetics and Cancer Cell Metabolism: Cross-talk and Therapeutic Opportunities

Apoptosis Targeting Therapeutics in Clinical Trials

Bentham Science Publishers

"Frontiers in Clinical Drug Research – HIV is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of acquired immune deficiency syndrome (AIDS) and other disorders associated with human immunodeficiency virus (HIV) infection. The scope of the book series covers a range of topics including the medicinal chemistry and pharmacology of natural and synthetic drugs employed in the treatment of AIDS (including HAART) and resulting complications, and the virology and immunological study of HIV and related viruses. Frontiers in Clinical Drug Research – HIV is a valuable resource for pharmaceutical scientists, clinicians and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in HIV/AIDS research.
The fifth volume of this series features 5 chapters that cover these topics: 
- Clinical Eradication of Latent HIV Reservoirs: Where Are We Now?
- HIV-1 Genotypic Drug Resistance Testing and Next-Generation Sequencing
- Current and Promising Multiclass Drug Regimens and Long-Acting Formulation Drugs in HIV Therapy
- Role of Nanotechnology in HIV Diagnosis and Prognosis
- Preventive and Therapeutic Features of Combination Therapy for HIV"


Frontiers in Clinical Drug Research - HIV: Volume 5

Atta-ur-Rahman

Frontiers in Clinical Drug Research – Hematology is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of hematological disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of anemias, coagulopathies, vascular diseases and hematological malignancies. Reviews in this series also include research on specific antibody targets, therapeutic methods, genetic hemoglobinopathies and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Hematology is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of hematology, oncology and vascular pharmacology.
 
 
 
The fifth volume of this series features 7 reviews with a focus on thalassemia treatment and preeclampsia among other topics.
 
 
 
- Recent advances in the diagnosis and management of pulmonary embolism
 
- An evidence-based approach to treatment with iron chelators in transfusion- dependent thalassemia patients: present trends and future scenario
 
- Current and future treatments of iron overload in thalassemia patients
 
- Preeclampsia: biological and clinical aspects
 
- Haematological modulations by fixed dose combination (FDC) of tramadol hydrochloride/paracetamol (THP)
 
- Possible use of eculizumab in critically ill patients infected with covid-19 role of complement c5, neutrophils, and nets in the induction DIC, sepsis, and MOF hematological markers
 
- Emerging diagnostic and therapeutic targets in preeclampsia

Frontiers in Clinical Drug Research - Hematology: Volume 5

Advances in Organic Synthesis is abook series devoted to the latest advances in synthetic approaches towardschallenging structures. The series presents comprehensive reviews written byeminent authorities on different synthetic approaches to selected targetmolecules and new methods developed to achieve specific synthetictransformations or optimal product yields. Advances in Organic Synthesisis essential for all organic chemists in academia and the industry who wish tokeep abreast of rapid and important developments in the field. This volume presents the following reviews:Electroluminescent polymers - a review on synthesis from organic compoundsRemarkable advances in the asymmetric synthesis of biologically active natural compounds from the advent of chiral auxiliariesThe chemistry of ynamides and their application in organic synthesisCarbon-heteroatom bond formation for medium ring heterocyclesTin(ii) salts: versatile and efficient lewis acid catalysts in reactions to add value to the glycerol and terpenic alcohols(E)-n-methyl-1-(methylthio)-2-nitroethenamine (nmsm) as a versatile ambiphilic synthon in organic synthesis


Advances in Organic Synthesis: Volume 13

"Frontiers in Cardiovascular Drug Discovery is a book series devoted to publishing the latest advances in cardiovascular drug design and discovery. Each volume brings reviews on the biochemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships of molecules used in cardiovascular therapy. The book series should prove to be of great interest to all medicinal chemists and pharmaceutical scientists involved in preclinical and clinical research in cardiology.
 
The fifth volume of the series covers the following topics:
 
-The Lipid Hypothesis: From Resins to Proprotein Convertase Subtilisin/Kexin Type-9 Inhibitors
-The Role of SGLT2i in the Prevention and Treatment of Heart Failure
-Natural Products and Semi-Synthetic Compounds as Antithrombotics: A Review of the Last Ten Years (2009-2019)
-Transient Receptor Potential Channels: Therapeutic Targets for Cardiometabolic Diseases?
-Treatment of Raynaud’s Phenomenon
-Traditional Medicine Based Cardiovascular Therapeutics
-Cardiovascular Disease: A Systems Biology Approach"


Frontiers in Cardiovascular Drug Discovery: Volume 5

Dr. M. lqbal Choudhary 

"Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology.
 
 
 
The seventh volume of this series features reviews that cover the following topics related to the treatment of neurodegenerative diseases, epilepsy and stroke:
 
-Fatty Acid Amides as a New Potential Therapeutic Agent in Multiple Sclerosis
 
-Epileptic Seizures Detection Based on Non-Linear Characteristics Coupled with Machine Learning Techniques
 
-Hampering Essential Tremor Neurodegeneration in Essential Tremor: Present and Future Directions
 
-The Potential Therapeutic Role of the Melatoninergic System in Treatment of Epilepsy and Comorbid Depression
 
-Modeling Neurodegenerative Diseases Using Transgenic Model of Drosophila
 
-Genetic Basis in Stroke Treatment: Targets of Potent Inhibitors"


Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7

 Zareen Amtul

"Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD), a disease that causes dementia, or loss of brain function. This disease affects parts of the brain that affect memory, thought, and language. Chapters in each volume focus on drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.
 
 
 
Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in the field of Alzheimer’s disease research.
 
 
 
The eighth volume of this series features chapters covering critical discussions on new therapies for AD. The reviews in this volume include:
 
- Novel Molecular Targets of Tauopathy; Therapeutic and Diagnostic Applications
 
- The Therapy of Alzheimer’s Disease: Towards a New Generation of Drugs
 
- Could Antibiotics Be Therapeutic Agents in Alzheimer’s Disease?
 
- Use of Antipsychotics in Patients with Alzheimer’s Disease
 
- Approaches Based on Cholinergic Hypothesis and Cholinesterase Inhibitors in the Treatment of Alzheimer's Disease
 
- Potential Biological Mechanisms with Prophylactic Action in Rapid Cognitive Impairment in Late-Onset Alzheimer's Disease"



Frontiers in Clinical Drug Research - Alzheimer Disorders Volume 8

"Frontiers in Clinical Drug Research – Anti infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology.
The second volume of this series features reviews that cover a variety of topics including: 
-Identification of nosocomial pathogens and antimicrobials using phenotypic techniques
-Topical antimicrobials
-Anti-infective drug safety
-Antimicrobial resistance
… and much more."


Frontiers in Clinical Drug Research - Anti Infectives: Volume 2

"Frontiers in Clinical Drug Research - Alzheimer Disorders is a book series concerned with Alzheimer's disease (AD), a disease that causes dementia, or loss of brain function. This disease affects parts of the brain that affect memory, thought, and language. Chapters in each volume focus on drug research with special emphasis on clinical trials, research on drugs in advanced stages of development and cure for Alzheimer’s disease and related disorders.
 
Frontiers in Clinical Drug Research - Alzheimer Disorders will be of particular interest to readers interested in drug therapy of this specific neurodegenerative condition and related brain disorders as the series provides relevant reviews written by experts in the field of Alzheimer’s disease research.
 
The seventh volume of this series features chapters covering critical discussions on AD biochemistry and new therapies. The reviews in this volume include:
- Deep Brain Stimulation in the Treatment of Alzheimer's disease
- ASS234: A New and Promising Anti-Alzheimer Agent
- Recent Advances in Alzheimer's Drug Discovery Research
- Alzheimer’s Disease and Proteasome: The Therapeutic Development and Management
- Alzheimer´s Disease: Fundamental Concepts, Novel Findings and Therapeutics Outcomes Coming from the Ca2+/cAMP Signalling Interaction
- Alzheimer's Disease: An Approach for Non-Pharmacological Therapies
- Past and Present Drug Development for Alzheimer's Disease.
 "

Frontiers in Clinical Drug Research - Alzheimer Disorders: Volume 7

Frontiers in Anti-Cancer Drug Discovery” is an Ebook series devoted to publishing the latest and the most important advances in Anti-Cancer drug design and discovery. Eminent scientists write contributions on all areas of rational drug design and drug discovery including medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. The Ebook series should prove to be of interest to all pharmaceutical scientists involved in research in Anti-Cancer drug design and discovery. Each volume is devoted to the major advances in Anti-Cancer drug design and discovery. The Ebook series is essential reading to all scientists involved in drug design and discovery who wish to keep abreast of rapid and important developments in the field.


Frontiers in Anti-Cancer Drug Discovery: Volume 2

Frontiers in Clinical Drug Research – Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases – diabetes and obesity. The scope of the series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs affecting endocrine and metabolic processes linked with diabetes and obesity. Reviews in this series also include research on specific receptor targets and pre-clinical / clinical findings on novel pharmaceutical agents. Frontiers in Clinical Drug Research – Diabetes and Obesity is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of diabetes and obesity research. The sixth volume of this series features 6 reviews which are informative guides to therapy and drug administration in diabetes and metabolic syndrome, for both the medical specialist and the pharmacologist. - The failing heart in diabetes with special emphasis on prevention- Flavonoids as prominent anti-diabetic agents- Chemosensor in glucose monitoring, advances and challenges - Synergistic drugs and polyherbal formulations for obesity: current status and future prospectives- Urge for herbal anti-diabetic medicines towards clinical and therapeutic implications- Curcuma longa as a dietary supplement and medication for diabetes mellitus: evidence from experimental studies


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Atta-ur-Rahman

Frontiers in Clinical Drug Research - HIV: Volume 5

Frontiers in Clinical Drug Research - Hematology: Volume 5

Advances in Organic Synthesis: Volume 13

Frontiers in Cardiovascular Drug Discovery: Volume 5

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 7

Frontiers in Clinical Drug Research - Alzheimer Disorders Volume 8

Frontiers in Clinical Drug Research - Anti Infectives: Volume 2

Frontiers in Clinical Drug Research - Alzheimer Disorders: Volume 7

Frontiers in Anti-Cancer Drug Discovery: Volume 2

Frontiers in Clinical Drug Research - Diabetes and Obesity: Volume 6

Atta-ur-Rahman